Trusted Resources: Education
Scientific literature and patient education texts
Emerging Treatments for Amyloidosis
source: Kidney International
year: 2015
authors: Sayed RH, Hawkins PN, Lachmann HJ
summary/abstract:Amyloidosis results from protein misfolding, and ongoing amyloid deposition can ultimately lead to organ failure and death. Historically, this is a group of diseases with limited treatment options and frequently poor prognosis. However, there are now ‘targeted’ therapeutics emerging in the form of stabilizers of the precursor protein, inhibitors of fibrillogenesis, fibril disruptors, and blockers of protein translation, transcription, and immunotherapy. We review many of these approaches that are currently being assessed in clinical trials.
organization: UCL Medical School, UKDOI: 10.1038/ki.2014.368
read more full text
Related Content
-
Recent Advances in Diagnosis and Treatment of Cardiac AmyloidosisCardiac amyloidosis (CA) has been believ...
-
Expanded Access to an Investigational Medical ProductSometimes called “compassionate use”...
-
Implanting Pacemaker Before Liver Transplant Does Not Lead to Better Outcomes, Study RevealsAlthough most patients with familial amy...
-
The Challenges in Chemotherapy and Stem Cell Transplantation for Light-Chain AmyloidosisLight-chain (AL) amyloidosis is a system...
-
Emerging Advances in the Management of Cardiac AmyloidosisAmyloidosis is a disease in which protei...
-
Amyloidosis: Coping With TreatmentEvery treatment can cause side effects o...
-
Wild Type ATTR Amyloidosis (Senile Systemic Amyloidosis)Amyloidosis is a rare disease caused by ...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences.
More information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences.
More information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.